Protocols
Hypothermia for Acute Ischaemic Stroke Trial - Edinburgh (HAIST-E)
A randomised pilot study of surface cooling to 35ºC or 33ºC degrees for 12 or 24 hours, with MR spectroscopy measurement of brain temperature
Hypothermia for Acute Ischaemic Stroke Trial - Utrecht (HAIST-U)
A randomised pilot study of surface cooling to 35ºC or 33ºC degrees for 12 or 24 hours
Protocol not available online
Malmö / Copenhagen Acute Stroke Cooling Trial (MASCOT)
A randomised pilot study of surface cooling to 33ºC for 24 hours in ventilated patients who have failed to improve with conventional therapy
Mild Hypothermia in Acute Ischemic Stroke: Safety and Feasibility Study (MHAIS)
A randomised pilot study of surface cooling to 35ºC for 12 hours in patients who have failed to improve within 2 hrs of tPA treatment.
A prospective, controlled,randomised trial comparing the feasibility, tolerability and safety of surface cooling (CSZ Blanketrol III) versus endovascular cooling (Zoll Thermogard XP) versus standard stroke treatment (ESO Guidelines).
Cooling in Intracerebral Hemorrhage (CINCH)
A prospective, multicentre German-Austrian randomised controlled trial of 50 patients with large primary ICH within 6 to 18 hours of onset treated with therapeutic hypothermia to 35ºC.
